To report annual experience of 20 children with recurring abdominal pain (RAP), endoscopic findings and the outcome of 2 weeks of treatment with omeprazole, clarithromycin and amoxicillin. Present Study was performed at Gujarat Adani Institute of Medical science Bhuj, Kutch, Gujarat, India from March 2014 to March 2015. For the duration of a 12- month period, 20 children (12 males and 8 females, aged 7-15 years) underwent endoscopy for assessment of RAP according to Apley's criteria. Every child was screened for the existence of serum specific IgG antibodies against HP antigens using an ELISA quantitative immunoassay method. Statistical analysis was performed with the help of SPSS version 15. Helicobacter pylori (HP) gastritis was evident in 8 (40%) patients of the 20 investigated. In two of the eight duodenitis was also observed. The endoscopic manifestation in five patients out of the eight (62.5%) was characterize by numerous small nodules covering most of the antral area and part of the distal area of the fundus. All patients had no symptoms after duration of two weeks of management which consisted of proton pump inhibitor, clarithromycin and amoxicillin. HP plays a role in childhood peptic ulcer disease. The endoscopic is suggestive of HP which plays a role in childhood peptic ulcer disease. Nodular gastritis (NG) is characterized by an abnormal goose-flesh manifestation on esophagogastroduodenoscopy (EGD). There is proof that Helicobacter pylori infection causes pathogenesis of NG. Because of asymptomatic manifestation, majority of cases are diagnosed accidentally,but some patients evince unusual upper gastrointestinal (UGI) symptoms such as indigestion, nausea, abdominal bloating, epigastric pain or abdominal discomfort. Endoscopically particular protrusions of the gastric antrum consist of fundic gland polyps, early gastric cancer, mucosaassociated lymphoid tissue lymphoma, intestinal metaplasia, and NG. NG is an atypical type of gastritis, with a reported incidence of 0.18-0.22%, but is comparatively frequent among young female patients. Biopsy should be done from protruded lesions when NG is alleged on endoscopy. Numerous studies are available to clarify the prevalence the prevalence of Helicobacter pylori infection and the linked symptoms in childhood. Previous studies have elucidated a revalence of HP gastritis of 30-60% in children with recurring abdominal pain (RAP) and HP was therefore understood to play a role in this indication complex. In children, epigastric pain, haematemesis and vomiting have been reported by some authors as symptoms that link to the HP infection, while many other authors have not found any precise symptoms. The macroscopic manifestation of nodular gastritis is a typical occurrence and often established in children infected by HP and is characterized by the manifestation of Lymph nodular hyperplasia of the antral mucosa. Present study was done with the aim to report annual experience of 20 children with RAP, endoscopic findings and the outcome of 2 weeks of treatment with omeprazole, clarithromycin and amoxicillin.

With Regards,
Sara Giselle
Associate Managing Director
Global Journal of Digestive Diseases