Endocervical type adenocarcinoma and adenocarcinoma in situ of the uterine cervix are similar morphologically to well-differentiated pancreatic adenocarcinoma. Natural killer cell-associated lymphoproliferative disorder includes NK/T cell lymphoma, nasal type, and aggressive NK cell leukemia, both of which have poor outcomes. In order to diagnose adenocarcinoma in the uterine cervix, an attentive immunohistochemically examination and a clear understanding of the patient's clinical information are required. NK-cell enteropathy or lymphomatoid gastropathy, on the other hand, is the name given to the benign NK cell proliferative lesion that has been identified in the gastrointestinal tract. We present a 33-year-old woman who presented with chronic cholecystitis and underwent cholecystectomy as a case of a similar CD56-positive NK-cell proliferative disorder affecting the gallbladder and gastrointestinal tract. There were a few scattered polyps in the gallbladder that were infiltrated by medium-sized atypical lymphoid cells that had eosinophilic cytoplasmic granules in their cytoplasm. The lymphoid cells were positive for T-cell-restricted intracellular antigen-1 and granzyme B on immunohistochemistry, but they were negative for myeloperoxidase. T-cell receptor gene rearrangement was polyclonal, and in situ hybridization was negative for Epstein-Barr virus-encoded RNA. There is no sign of lymphoma during the patient's 36-month close observation. Nodular fasciitis in children is uncommon and typically affects the head and neck. Event in other anatomic areas is phenomenal. This case of nodular fasciitis involves a newborn infant who presented with a rapidly expanding mass in the hand. On T1-weighted MRI images, it was heterogeneously isointense, while on T2-weighted images, it was hyperintense. Consistent with a nodular fasciitis, histological examination revealed short, intersecting fascicles of uniformly spindled myofibroblasts embedded in a myxoid to collagenous stroma. However, due to its rapid growth, vigorous mitotic activity, and focally infiltrative architecture, the lesion was initially identified as an infantile fibro sarcoma. This study shows that atypical nodular fasciitis presentations can lead to misdiagnosis.

With Regards,
Sara Giselle
Associate Managing Editor
 Journal of Critical Care Obsestrics & Gynocology