HER2 Gene Status of Breast Cancer Specimens

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The economics of the process, the importance of integration with LIS and MIS, errors and the principles of their solution, payback, and every stage of laboratory work will be considered in detail. Additionally, all advantages and disadvantages of digitization, peculiarities of using technology, differences from the conventional approach to diagnostics, and differences from the conventional approach will be discussed. from diagnosis and archiving to logistics and registration. We will present a comprehensive analysis of statistics and observations on how to organize processes in a fully digital laboratory because all data has been digitized over several years. The high cost-effectiveness of the platform and approach, which enabled us to compete successfully in the market, is an important aspect of our experience. The survey of physicians' attitudes toward digital pathology's findings will also be presented. The uPath HER2 Dual ISH Image Analysis for Breast algorithm was developed to assist pathologists in determining the HER2 gene status of breast cancer specimens. This study sought to contrast manual read scoring with uPath HER2 DISH image analysis for VENTANA HER2 DISH-stained breast carcinoma specimens using the Ground Truth (GT) gene status as a reference. 220 Formalin-Fixed, Paraffin-Embedded (FFPE) breast cancer cases were examined by three reader pathologists using both manual and uPath HER2 DISH IA techniques. The GT gene status determined by a panel of pathologists was compared to the scoring results from computer-assisted scores (IA) and manual read scores (MR). The distinctions in understanding paces of HER2 quality status between manual, PC helped, and GT quality not set in stone. Overall, our data support the uPath HER2 DISH IA's use as an aid for pathologists in routine breast cancer diagnosis because it is comparable to manual scoring.

With Regards,
Sara Giselle
Associate Managing Editor
 Journal of Critical Care Obsestrics & Gynocology