Safe related unfriendly occasions because of resistant designated spot inhibitors are seen in foundational organs; the rate of endocrine problems is accounted for to be 3.8-29%. In any case, thyroid problems are the most widely recognized, while the frequency of pituitary issues isn't as high. Nivolumab treatment was started in a 42-year-old male patient due to repetitive oropharyngeal squamous cell carcinoma. Following four months, he encountered checked discomfort, and blood tests uncovered diminished degrees of both adrenocorticotropic chemical and cortisol. From the above discoveries, pituitary-adrenal inadequacy was analyzed, and glucocorticoid substitution treatment was started. This brought about a quick improvement in the side effects. The patient is as of now going through treatment while still on proceeded with glucocorticoid substitution treatment. Discomfort is a side effect that is capable by all malignant growth patients; as it's anything but a trademark side effect of endocrine problems, we will generally consider it as inconsequential. In any case, when an ICI is utilized, the beginning of endocrine problems is constantly thought, and it is significant not to disregard the quick expansion of chemical tests. Legitimate conclusion of resistant related unfavorable occasions and fast commencement of treatment are valuable to the patient even concerning hostile to cancer viability with proceeded with ICI treatment.Occipital neuralgia is an excruciating condition influencing the back scalp in the conveyances of the more noteworthy occipital nerve lesser occipital nerve third occipital nerve or a blend of the three. Scalp masses can be a reason for occipital neuralgia in the event that they start from brain parts, yet their rate is low and preoperative determination might be troublesome. Among cancers of fringe nerves, there is a gathering starting from Schwann cells. We report an intriguing instance of a schwannoma causing occipital neuralgia. Chinese woman gave a half year of everyday migraines essentially in the left occipital locale, with no other related side effects. Actual assessment was ordinary.

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With Regards,
Sara Giselle
Associate Managing Editor
Journal of Medical Physics and Applied Sciences